Therapeutic Depletion of Natural Killer Cells Controls Persistent Infection

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Therapeutic depletion of natural killer cells controls persistent infection.

Persistent viral infections are associated with host and viral factors that impair effective antiviral immunity. Natural killer (NK) cells contribute to establishment of persistent lymphocytic choriomeningitis virus (LCMV) infection in mice through suppression of virus-specific T cell responses during the first few days of infection, but NK cell depletion during those early time points can enab...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2013

ISSN: 0022-538X

DOI: 10.1128/jvi.03002-13